Alcoholism: modest role seen for genes.
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منابع مشابه
Alcoholism – the Worst Addiction
Introduction: The most common substance of abuse/dependence in patients presenting for treatment in western countries is alcohol. Ethyl alcohol or ethanol which is also called medicinal alcohol is used as an official drug compendium. It is also administered as an antidote in methanol poisoning. However, regular consumption of high amounts of alcoholic drinks induces dependence and addiction lea...
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The chronic high-level alcohol consumption seen in alcoholism leads to dramatic effects on the hippocampus, including decreased white matter, loss of oligodendrocytes and other glial cells, and inhibition of neurogenesis. Examining gene expression in post mortem hippocampal tissue from 20 alcoholics and 19 controls allowed us to detect differentially expressed genes that may play a role in the ...
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Diagnosis is the process of identifying and specifying the necessary condition. In clinical research, diagnostic criteria are a set of rules needed for identification. These are important and improvement of diagnostic criteria often precedes other major advances in understanding other areas viz. aetiology and treatment. As regards diagnosis of alcoholism, there are several criteria and definiti...
متن کاملConvergence of genome-wide association and candidate gene studies for alcoholism.
BACKGROUND Genome-wide association (GWA) studies have led to a paradigm shift in how researchers study the genetics underlying disease. Many GWA studies are now publicly available and can be used to examine whether or not previously proposed candidate genes are supported by GWA data. This approach is particularly important for the field of alcoholism because the contribution of many candidate g...
متن کاملAssociation between Alcoholism and the Genetic Polymorphisms of the GABAA Receptor Genes on Chromosome 5q33-34 in Korean Population
Family, twin, and adoption studies have demonstrated that genes play an important role in the development of alcoholism. We investigated the association between alcoholism and the genetic polymorphisms of the GABAA receptor genes on chromosome 5q33-34 in Korean population. The genotype of the GABAA receptor gene polymorphisms were determined by performing polymerase chain reaction genotyping fo...
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ورودعنوان ژورنال:
- Science
دوره 255 5044 شماره
صفحات -
تاریخ انتشار 1992